![]() In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. ![]() Lidocaine may be absorbed following topical administration to mucous membranes, its rate and extent of absorption depending upon the specific site of application, duration of exposure, concentration, and total dosage. Hydrocortisone acetate has a chemical name pregn-4-ene-3, 20-dione, 21-(acetyloxy)-11,17- dihydroxy-(11ß). ![]() Lidocaine is chemically designated as acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl), and has the following structure: Hydrocortisone acetate provides relief of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Product releases lidocaine to stabilize the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action. CLINICAL PHARMACOLOGY: MECHANISM OF ACTION: Related/similar drugs hydroxyzine, hydrocortisone topical, Benadryl, lidocaine topical, diphenhydramine, phenylephrine topical, Anusol-HC INACTIVE INGREDIENTS:Īluminum sulfate, calcium acetate, carbomer 980, cetyl alcohol, citric acid, glycerine, methylparaben, mineral oil, polycarbophil, propylene glycol, propylparaben, purified water, sodium citrate, sodium lauryl sulfate, sodium hydroxide, sorbitan stearate, stearic acid, stearyl alcohol, trolamine, urea, and white petrolatum.
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